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doi:10.1172/JCI110155

Curr Diabetes Reports

They also require ongoing maintenance since the effect wears off as the neurotoxin metabolizes

Peptides discussed here are not FDA-approved for human therapeutic use

Many protocols start at the lower end and adjust based on the specific research objectives

Common, harmless side effects Water retention (GH peptides): Mild puffiness, especially in hands/feet Temporary (resolves within weeks) Not dangerous Reduce dose if bothersome Injection site reactions: Slight redness or bump at injection site Temporary Rotate sites to minimize Not concerning unless severe Initial fatigue (GH peptides): First 1-2 weeks Body adjusting to increased GH Improves with time Take peptides before bed Increased hunger (GHRP-6): Expected with GHRP-6 Manage with meal timing Switch to Ipamorelin if problematic These are normal and not cause for alarm