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This was accompanied by HMGB1 and PD-L1 upregulation, suggesting that ferroptosis enhances immune activation while modulating checkpoint signals

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Some clinical studies have found that GHK-Cu-based creams produced results comparable to vitamin C and retinoids, without causing irritation

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doi: 10.1007/BF00027124 69 HsuP

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however, a previous analysis has suggested that the actual prevalence may be 10 times this estimate, most likely because of underdiagnosis (8)

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Morota S, Mnsson R, Hansson MJ, Kasuya K, Shimazu M, Hasegawa E, et al

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Cell 84 , 552569.e11 (2024)

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