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In addition, when AOD 9604 is part of a program with adequate nutrition and supplements, it would be expected to support people who have experienced long-term gradual weight loss

Long-term safety beyond 12 weeks has not been formally studied in large populations

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Its effects on energy metabolism and related biology are mediated through specific enzymatic and metabolic pathways

Human studies have shown that PYY delays gastric emptying and promotes satiety (165), while short-term intravenous administration of PYY3-36 , at doses generating physiologic postprandial blood excursions, was shown to decrease calorie intake by approximately 30% in lean and obese subjects, without causing nausea, affecting food palatability, or altering fluid intake, nor was it followed by compensatory hyperphagia (166)

[5] This is an emerging area of interest, particularly for patients dealing with both excess weight and degenerative joint disease