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Currently, flow cytometry combined with fluorescence 10 , ICP-MS imaging 19 , Raman 11 and microfluidic technology 11,20 have been used to reveal tumor heterogeneity according to the specificity of cell-surface receptors

In human fibroblast cultures, this has been shown to extend the "Hayflick limit" (the number of times a cell can divide) by over 10 passages

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