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Nephron

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Inflammation, oxidative stress, and fibrosis are intricately associated processes in the etiopathogenesis of CKD [7]

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The eyes may also be inflamed

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Odegard, Koichi Yuki, Sophia Koutsogiannaki Critical Care.2025;[Epub] CrossRef Effects of antidiabetic medications on the relationship between type 2 diabetes mellitus and cognitive impairment Annalisa Cozza, Chiara Chinig, Elvira Filicetti, Giada Ida Greco, Rosamaria Lappano, Cinzia Marinaro, Lucia Muglia, Luca Soraci, Andrea Corsonello, Fabrizia Lattanzio, Mara Volpentesta Ageing Research Reviews.2025

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In conclusion, these data support a mechanism whereby SP3N induces proximity between FKBP12 and FBXO22 to prompt FKBP12 degradation by FBXO22

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