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Thus, the intracellular signaling which results in hepatocyte necrosis after APAP could also influence inter-cellular communication through various gap junction proteins and further research in this area will provide additional insight into the transmission of APAP- induced signaling across the liver

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191 CoQ10 also has well-documented anti-inflammatory effects, and has been shown to reduce the inflammatory markers CGRP and TNF- in people with migraine

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