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Some studies suggest that oral administration and metabolic processing (methylation, conjugation, etc.) is necessary, and have identified quercetin derivates, which display variable T max , as responsible for a cooperative antiviral activity (126128)

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doi: 10.3390/ijms23063138 153 ChenRZouJKangRTangD

After the initial infection of the skin (stage 1), the spirochete often disseminates to many sites (stage 2), particularly to other skin sites, the nervous system, heart or joints, where it might cause persistent infection (stage 3) for years