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F.et al (2021a)

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If supportive measures such as supplementation, topical therapy, or sun protection are discontinued, pigmentation may gradually recur

Cats with CKD fall into four stages progressively advancing to the final stage, Stage 4 (where cats can live a maximum of 35 days): Source: Northern Suburbs Veterinary Hospital In the final stage, Stage 4, the symptoms to look for include: Refusal to eat or drink, an inability to walk, continued weight loss, vomiting, incontinence, confusion, hiding, restlessness, seizures, and/or shortness of breath

The result is thicker, more resilient skin with improved hydration and texture over a series of treatments

Giles FJ, Miller CB, Hurd DD, Wingard JR, Fleming TR, Sonis ST, Bradford WZ, Pulliam JG, Anaissie EJ, Beveridge RA, Brunvand MM, Martin PJ, PROMPT-CT Trial Investigators: A phase III, randomized, double-blind, placebo-controlled, multinational trial of iseganan for the prevention of oral mucositis in patients receiving stomatotoxic chemotherapy (PROMPT-CT trial)