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However, accumulation of metabolites in this pathway did correlate with BUN and creatinine, consistent with a role of renal dysfunction in regulating circulating levels of oxidized purines

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Found in every cell of the body, glutathione plays a crucial role in various physiological processes, including: Detoxification: Glutathione aids in the detoxification of harmful substances, including heavy metals, environmental toxins, and even byproducts of metabolism

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Most glutathione is maintained as GSH in healthy humans and animals, with GSSG concentrations generally being low