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Description

5 , e1250 (2014)

At least five variants of GPx are known to be selenoproteins: GPx1 (in the cytosol) GPx2 (specific to epithelial cells in the lungs and intestinal lining) GPx3 (thyroid and kidneys) GPx4 (phospholipid-hydroperoxide) and GPx6 (active in the olfactory epithelium)

Cheuk, D

Personalized medicine, by considering genetic variations affecting antioxidant enzyme function or stress response pathways, could enhance oxidative stress therapies and potentially improve treatment outcomes

Studies have looked at AHK-Cu's interaction with Wnt signalling, a cellular pathway involved in hair follicle development and cycling

the GSSG has less toxicity than ROS-products of GSH, and indeed GSSG is known to be absorbed and available for hepatic reduction to GSH, though at the cost of increased metabolic load with respect to GSH administration