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These enzymes constitute the first line of cellular defense against reactive oxygen species (ROS) and oxidative damage to cellular macromolecules

Here we find increased proportion of pro-inflammatory and mesenchymal fibroblast subpopulations and senescent fibroblasts, and enhanced expression of senescence-associated secretory phenotype genes using single-cell RNA sequencing analysis, as well as elevated p16 protein and more -galactosidase-positive cells in keloids

Peptides and peptidomimetics as inhibitors of protein-protein interactions involving -sheet secondary structures. Current opinion in chemical biology vol

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doi: 10.1007/s10517-015-3062-y