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The findings of some of the clinical trials in which lipoic acid administration has been tested in diabetic patients during the last 10 years are summarized

Quintanilla-Licea R, Vargas-Villarreal J, Verde-Star MJ, Rivas-Galindo VM, Torres-Hernndez D (2020) Antiprotozoal activity against Entamoeba histolytica of flavonoids isolated from Lippia graveolens Kunth

Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses

Vitamin C & E

This suggests that the cells rely on GPX4 to resist oxidative stress, and this could potentially increase their sensitivity to RSL3, a ferroptosis inducer that targets GPX4

Interestingly, daily treatment of hypophysectomized rats for 3 weeks with rat growth hormone caused a 1.7-fold increase in penis weight and a 1.4-fold increase in penile AR levels over saline-treated hypophysectomized rats in the absence of androgens (unpublished data)