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There is a growing number of studies testing the effects of N-acetylcysteine in people with psychiatric or neurological diseases (12)

Together, they produce comprehensive results that neither achieves independently

Cuellar, T

B., Zeitlin, S

The PINK1/Parkin-mediated mitophagy is triggered when PINK1 is stabilized on the outer membrane of damaged mitochondria and recruites Parkin, an E3 ubiquitin ligase, followed by ubiquitination of mitochondrial proteins, which are then recognized by autophagy receptors [41]

Compared with the D/A and LRKY/AAAA mutants, the FIL/AAA and GK/AA mutants presented significantly weaker proteinprotein interactions, further confirming the importance of FIL residues but not residues in the TM4 region in homotrimer formation (Supplementary Fig