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Methylmalonic Acid (MMA) and Homocysteine Tests : These are the key players for sniffing out a hidden B12 deficiency

Face serums and creams: Clinical standard: 1-3% concentration Maximum typically used: 4% concentration Application: Once or twice daily Duration: Minimum 8-12 weeks for visible results Eye area products: Concentration: 1-2% (lower for sensitive periorbital skin) Application: Once daily, typically evening Amount: Pea-sized for both eyes Scalp solutions for hair: Concentration: 0.5% solution common Application: 1-2ml to affected areas once or twice daily Duration: 3-6 months minimum for meaningful changes Higher concentrations do not always mean better results with topicals

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It is not available as a licensed medicine through the NHS or any regulated UK pharmacy

Never inject into the same spot twice in a row

However, a disadvantage of these small molecules is their uncontrolled toxicity, which results in severe side effects