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Naltrexone May Increase Growth Hormone Some studies suggest that Naltrexone can boost growth hormone levels, which is crucial for building and maintaining lean muscle mass and increasing fat burning

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doi: 10.3389/fmed.2016.00038 23

AOD-9604 acts on lipid metabolism at the fat-cell level

This was because the drug did not significantly reduce weight in 536 subjects over the course of 24 weeks 2

Engages the pituitary GHRH receptor, triggering natural, pulsatile GH release that aligns with physiological secretion patterns