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Nat Genet 2013;45(11):1284-92

In addition, ADCs can also exert an extracellular action on neighbouring cells via the release of the payload after intracellular cleavage of the linker (bystander effect), which is mediated by the proteases localised in lysosomes

Dietary supplementation with ethyl eicosapentaenoate, an omega-3 fatty acid derivative, was assessed in a randomized, double-blind phase III trial involving veterans with mild cognitive impairment