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Oxidative stress has been demonstrated to enhance the activity of protein arginine N-methyltransferase (PRMT) and reduce the activity of dimethylarginine dimethylaminohydrolase (DDAH), an ADMA-degrading enzyme, thus resulting in a rise in ADMA concentrations [69, 151, 152]

30 Vials

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A pooled analysis of ARIC and KIHD studies showed that baseline and long-term GGT predicted the risk of atrial fibrillation with fully adjusted HR of 1.09 (1.021.16) and 1.14 (1.031.25), respectively, per each SD higher baseline and long-term GGT (66)

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