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Serotonin acts together with dopamine to modulate octopaminergic and tyraminergic neurons, and serotonin also acts on other neuronal targets to regulate behavior

Daly A, Gokmen-Ozel H, MacDonald A et al

Comparative studies using GHRP-2 as reference have generated fundamental insights into GHS-R1a pharmacophore requirements for potency, selectivity, and HPA axis co-stimulation findings that underpin rational peptide drug design across the GH secretagogue field

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And the landmark 2014 paper that established how dihexa was supposed to work in the brain was retracted by the journal in 2025

Scientific investigations have highlighted the significant role of p62 in a spectrum of diseases, such as tumours, neurodegenerative disorders, and inflammatory conditions [127,128,129]