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Early and progressive impairment of spinal blood flow-glucose metabolism coupling in motor neuron degeneration of ALS model mice

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There was no significant association between white matter hyperintensity burden and CSVD features such as lacunes and enlarged perivascular spaces and pial collateral supply

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Subsequent laboratory studies have explored its observed effects on senescent chondrocytes, endothelial cell senescence via p53 signaling, and senescent cancer-cell models

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