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Oxid Med Cell Longev 2021(1):6635460 Mathur A, Pandey VK, Kakkar P (2018) Activation of GSK3/-TrCP axis via PHLPP1 exacerbates Nrf2 degradation leading to impairment in cell survival pathway during diabetic nephropathy

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Front Endocrinol (Lausanne) (2017) 8:337

By selectively inhibiting SHMT enzymes, SHIN1 attenuates STAT3 and STAT1 signaling pathways associated with IFN- and IL-22, normalizes keratinocyte proliferation and differentiation, and suppresses pathogenic inflammatory programs

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