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Dihydroartemisinin ameliorates psoriatic skin inflammation and its relapse by diminishing CD8(+) T-cell memory in wild-type and humanized mice

Conversely, M2 macrophages demonstrate diminished antigen-presenting capacity, releasing anti-inflammatory cytokines like interleukin (IL)-10 or TGF-, and suppressing immune responses [122]

Mutations disrupting another interface in SERF2 (K23, G24, and K25) also weaken rG4 binding, while mutating all conserved lysine residues in both binding interfaces further reduces rG4 binding

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10.1208/s12249-011-9584-3 14 AppellM.EvansK

Available via Accessed 15 Jan 2020:16 Cacciatore I, Cornacchia C, Pinnen F, Mollica A, Di Stefano A (2010) Prodrug approach for increasing cellular glutathione levels