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Several trials, including a maximum of a few tens of HF patients, supplemented with thiamine (dose ranging from 100 mg to 300 mg per day), reported a significant increase in left ventricular ejection fraction after several weeks of supplementation [153,164,165]

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If a deficiency is linked to a chronic condition like pernicious anemia, Crohns, or celiac disease, you might need injections for the long haul to bypass the digestive system entirely

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doi:10.1016/S2213-8587(21)00203-5 Baggio LL, Drucker DJ