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GSH, for example, is an abundant tripeptide in the cytoplasm that acts as a hydrogen donor from its thiol group (-SH), regenerating antioxidants such as vitamins C and E, as well as participating directly in the neutralisation of peroxides and free radicals [18]

Due to the importance of phase 2 metabolites, treatment with glucuronidase and arylsulfatase is often applied during the analysis of urine and blood samples to reduce the number of required reference standards and to improve sensitivity

NPJ Regen Med 7:16 Lu P, Takai K, Weaver VM, Werb Z (2011) Extracellular matrix degradation and remodeling in development and disease

26 Such fragmentation is closely associated with the dysfunction of endothelial cells and is now considered an important precursor of atherosclerosis

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