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Description

Genes that were differentially expressed (a P value cut-off of 0.05 and a fold-change cut-off of 2) between the two groups were analysed using the DESeq2 package

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The final pellet was dissolved in guanidine HCl, and absorbance was measured at 370 nm [15]

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Table 2: Summary of in vivo studies with fertility endpoints for chemical inhibitors or gene knockout experiments as evidence to support the essentiality of KEs

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Results: In livers of humans and mice with MASH, AGXT was suppressed due to promoter hypermethylation, and LDHA activity was enhanced, leading to a marked increase in hepatic oxalate in association with disease severity

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