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When the drug binds to its targets, it disrupts the EGFR and MET signaling process that helps drive EGFR-mutant NSCLC

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82 A separate mention should be made of acute aortic dissection, an extremely severe condition for which a rapid diagnosis is essential

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GI side effects were the most common and typically mild to moderate

Widespread use of DOACs began in 2010 due to multiple factors, including 421 : Standardized dosing Decreased frequency of follow-ups Less adverse effects Fewer medication and food interactions Quicker onset of action Because of these factors, DOACs are generally preferred over warfarin by both patients and physicians