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The WHI used synthetic conjugated equine estrogens plus medroxyprogesterone acetate in women who were on average 63 years old over a decade past menopause

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Most chronic injuries fail to heal because the environment around the injury never becomes favorable for durable remodeling

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However, lixisenatide in the ELIXA trial did not significantly alter the incidence of MACE, and exnatide in the EXSCEL trial lower the risk of MACE with no significant difference