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could not demonstrate any benefit of NAC treatment, compared with placebo, on lung function, quality of life, or inflammatory markers in patients with sarcoidosis-associated ILD (148)

Ongeveer 1-3% van de opgenomen zuurstof wordt omgezet in radicalen.(1) Een te hoge productie van radicalen en/ of te lage spiegels van antioxidanten leidt tot oxidatieve stress: het verdedigingssysteem van antioxidanten is ontoereikend om ongewenste oxidatieve beschadiging van vitale cel- en weefselstructuren te voorkomen.(2,3) De (cumulatieve) oxidatieve schade draagt bij aan biologische veroudering en vergroot de kans op ziekte(progressie)

Traditional oral forms tend to have lower bioavailability because glutathione is broken down by enzymes in the digestive tract before reaching the bloodstream

Plant Soil 419 (1), 153167

219,222 Psyllium ( Plantago ovata ) is regarded as safe for pregnancy-related constipation due to its bulk-forming, non-absorbed nature, with minimal adverse effects