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But they come with a caveat that rarely gets the attention it deserves: up to 30 to 40% of that weight loss can come from lean muscle mass rather than fat tissue

You just have to know when youre working from robust human data, versus extrapolating from mouse models

NNMT protein expression in muscle tissue was significantly greater in aged (27-mo old C57BL/6 mice) compared to young (3-mo old C57BL/6 mice) individuals ( FIG

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