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Description

Fragment-based ligand discovery applied to the mycolic acid methyltransferase Hma (MmaA4) from Mycobacterium tuberculosis : a crystallographic and molecular modelling study

It supports energy production through fatty acid metabolism, not through stimulants like caffeine

R is the measured 405/488 nm ratio of roGFP2 in the respective bacterial strain under the respective condition

Intracerebroventricular KYNA infusions similarly impair conditioned orienting to visual cues, highlighting its role in disrupting attentional processing and implicating glia-derived KYNA in cognitive deficits relevant to neuropsychiatric and neurodegenerative disorders [76]