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The Reality of Randomized Controlled Trials for Assessing the Benefit of Proton Therapy: Critically Examining the Intent-to-Treat Principle in the Presence of Insurance Denial

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While mitochondrial ROS (mROS) have been implicated as critical mediators of LPS-induced bactericidal activity in macrophages (37, 38), our findings demonstrate that MPLA-induced antimicrobial responses occur independently of mROS

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We examined the role of this predicted motif in the activity of LnaB by creating substitution mutants for each of these residues and testing their activity in converting PR-Ub into ADPR-Ub