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Additionally, it has been shown that sleep deprivation accelerates aging through disrupting the redox homeostasis dominated by non-radicals

This is often referred to as a washout period

Round EK, Chen P, Taylor AK, Schmidt E

The mass spectrometer was operated using Tune v3.5.3881.18

11 Further evidence for increased oxidative stress has been demonstrated in the rodent PPA model, including increased brain protein carbonylation and lipid peroxidation, altered phospholipid profiles and increased activated microglia