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doi: 10.1111/j.1600-0404.1975.tb05777.x

Nonmuscle Myosin II Activation Regulates Cell Proliferation, Cell Contraction, and Myofibroblast Differentiation in Keloid-Derived Fibroblasts

Additionally, the altered ECM affects tissue vascularization and oxygenation, contributing to hypoxia, which further exacerbates the fibrotic process (93)