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In groups supplemented with vitamin E, levels of oxidative stress markers were decreased, and a reduction in vitamin E concentration contributed to the progressing of AD in dogs (164)

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Sporadic Alzheimer disease fibroblasts display an oxidative stress pehnotype

A further small study done recently on 10 paediatric patients similarly found that intranasal OH-Cbl normalised serum B12 levels in deficient patients ( Subcutaneous B12 Subcutaneous B12 is occasionally used, especially in patients with inborn errors of cobalamin metabolism, who need high pharmacological doses of B12 to maintain their B12-dependent metabolic pathways and related biochemistry within normal range

10.1016/S0091-3057(01)00525-1 178 TanowitzM.Von ZastrowM

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