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Integrin and microtubule crosstalk in the regulation of cellular processes

Although alterations in post-translational modifications have been reported to contribute to abnormal protein dynamics, cellular disturbances, and disease, how protein SUMOylation benefits CCA progression and modulates the interaction between transformed biliary cells and the tumour microenvironment (TME) remains unexplored

J Ethnopharmacol (2021) 266:113434

In the pathological environment of RA, due to synovial inflammation, the osteoclast-osteoblast axis is severely disrupted, leading to enhanced osteoclast function and RA-related bone destruction 10

However, an elevation of B12 in ones serum can be tied to the MTHFR gene variation , as those with the MTHFR gene variation may be unable to properly use non-methylated B12

What is the mechanism by which H