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Phosphofurin acidic cluster sorting protein 2 (PACS-2) is a versatile sorting protein involved in the regulation of lipid metabolism, apoptosis and autophagy (30)

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Specific depressed NF- activation in cells treated with TNF- by hGH As inhibition of NF- B activation was clearly linked to increased apoptosis of various tumour cells, we decided to test NF- B DNA binding activity in nuclear extracts from our cell lines incubated with TNF- , a potent NF- B stimulator (Baeuerle and Baltimore, 1988)