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The main sites of mitochondrial ROS production are complex I (NADH dehydrogenase) and complex III (cytochrome bcI complex)

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87 As noted earlier, high levels of aldehyde dehydrogenase in the GI and hematopoietic cells can protect cells by detoxifying metabolites of cyclophosphamide

Carcaterra and Caruso, 2021)

PLoS ONE 9 , e98186 (2014)

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