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et al (2014) J Biol Chem

In a Medicare cohort, dementia prevalence rose from 28% at age 66 to 70% by age 80 in schizophrenia, compared with 1.3 and 11.3% in matched controls (12)

Metallothionein-1G (MT1G) have a high content of cysteine residues that bind various heavy metals, these proteins are transcriptionally regulated by both heavy metals and glucocorticoids, such as iron, zinc and copper 8