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Increased GST and/or GT tumor expression, generally considered as a bad prognosis marker (associated with drug resistance and disease progression), and could potentially be used as a predictive marker, allowing doctors, after biopsy, to identify which patients will respond best to GST or GT-activated prodrugs

This process regulates the miR-770-3p/triggering receptor expressed on myeloid cells 2 (TREM2) axis, thereby promoting microglial transition from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype, which alleviates cognitive impairment and neuronal damage in AD mouse models [191]

(Deficiencies in these vitamins can lead to various health issues, such as fatigue, weakness, anemia, nerve damage, skin disorders and cognitive problems.) Energy production- B vitamins are essential for converting carbohydrates, fats, and proteins into energy

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Aquacult Int 4:3141 Tsangaris C, Papathanasiou E, Cotou E (2007) Assessment of the impact of heavy metal pollution from a ferro-nickel smelting plant using biomarkers

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