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Caino MC, Ghosh JC, Chae YC et al (2015) PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion

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Currently, dopamine-based therapies such as levodopa are used to alleviate early motor symptoms of PD, but these treatments have significant side effects and do not halt disease progression (Borovac, 2016)

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In addition, KDM4C knockdown led to a significant increase in H3K9me3, and this increase in H3K9me3 was not significantly reversed upon aKG supplementation, indicating that KDM4C is required for the Gln-mediated epigenetic regulation of cFLIP (Fig