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Cisplatin also affects calcium signaling pathways and the function of several protein kinase families, including the MAPK (mitogen activated protein kinases), JNK (c-Jun N-terminal kinase o), PKC (protein kinase C) and AKT (serine/threonine kinases) leading to cell death (Dasari and Tchounwou, 2014)

Risk factors for severe bleeding complications in percutaneous renal biopsy

[DOI] [PubMed] [Google Scholar] 116.Du Y., He W., Zhou W., Li X

Persistent exposure or poor clearance may increase methylation demand, elevate SAH, consume glutathione precursors and impair response to otherwise appropriate nutrient therapy