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SN Appl Sci 2:1202 Bordbar AK, Rastegari AA, Amiri R, Ranjbakhsh E, Abbasi M, Khosropour AR (2014) Characterization of modified magnetite nanoparticles for albumin immobilization

One group of mice was fed an adequate selenium diet and another group a deficient selenium diet

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Phase 2 trial (NEJM 2023) used a structured ramp to 12 mg/week but at trial doses of 8 mg and 12 mg, dropout from gastrointestinal events was substantial