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The ability of these neoantigens to evoke such responses in patients with LS-CRC, as well as in individuals with LS who have yet to develop LS-associated cancers, suggests that they may be potential effective targets for vaccine-based therapy

Am J Respir Cell Mol Biol 41:722730

Activation of the NLRP3 inflammasome represents a key step in IL-1 production during HIRI, further promoting neutrophil recruitment and amplification of the inflammatory response (45)

& Castelo-Branco, G

UA levels also have the potential to serve as a promising biomarker for identifying individuals at high risk of neurodegenerative diseases and could be a novel target for pharmacological therapy

In addition, CuPDTC is also engaged in induction of protein cleavage during apoptosis