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Dauer W, Kholodilov N, Vila M, Trillat AC, Goodchild R, Larsen KE, Staal R, Tieu K, Schmitz Y, Yuan CA, Rocha M, Jackson-Lewis V, Hersch S, Sulzer D, Przedborski S, Burke R, Hen R, 2002

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Consequently, the requisite calcium level is constrained to remain below 1.5 mmol/L to maintain normal muscle physiology, resulting in afflicted animals assuming a protracted recumbent posture (89)

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Actually the structures of U46C GPx4 mutant and rhGPx3 mutant are quite similar (Figure 4a) although their sequence identity is only 34%