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In addition, the mice experienced significant fat loss, reduced adipocyte size and volume, and decreased triglycerides and free fatty acids [10]

The worst plausible outcome is no benefit, not harm

In its dry form, B12 is remarkably stable against both heat and light

Additionally, it is one of the nine essential amino acids in the human body

Preclinical studies indicate that NNMT knockdown or inhibition can protect against diet-induced weight gain and improve metabolic parameters without reducing food intake [8] [9]

Parsons RB, Aravindan S, Kadampeswaran A, Evans EA, Sandhu KK, Levy ER, Thomas MG, Austen BM, Ramsden DB (2011) The expression of nicotinamide N -methyltransferase increases ATP synthesis and protects SH-SY5Y neuroblastoma cells against the toxicity of complex I inhibitors