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doi: 10.1016/j.apjtb.2017.09.024 23

Even in trials that showed a benefit, not every participant responded the same way, and the effect was modest tone-evening not a fundamental colour change

2011, doi:10.1186/1475-2891-10-75 Duntas, L H

In contrast, the small-volume sampling strategies discussed here are intended for decentralized, user-operated measurements of one or a few targeted biomarkers at the point of care

Regarding the mechanisms, prolonged periods of fasting state are characterized by a metabolic switch from glucose dependency to elevation of lipid metabolism, including free fatty acid usage and production of ketone bodies in the liver (Hofer et al., 2022)