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Bleomycin-induced mouse fibrosis model and administration of anti-CD38 antibodies All animal studies were conducted in accordance with NIH guidelines for the care and use of laboratory animals and animal protocols were institutionally approved by the Animal Care and Use Committees of Northwestern University and the University of Michigan

Key considerations include protein intake (amino acids for collagen synthesis), vitamin C (essential cofactor for collagen production), zinc (supports immune function and protein synthesis), and omega-3 fatty acids (anti-inflammatory effects)