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As the pathologic progress continues, the neurodegeneration of formerly impaired regions is also aggravated (Braak et al., 2020)

Zhao Y, Zhao B, Wang X, Guan G, Xin Y, Sun YD, et al

25:150923 Belani MA, Shah P, Banker M, Gupta SS

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10.1152/ajpheart.00080.2013 206 Vila-PetroffM

The authors reported that AOD-9604 stimulated lipolysis in isolated adipocytes and that chronic daily treatment in obese Zucker rats produced reductions in body weight gain of more than 50% relative to untreated controls over the treatment period, without effects on insulin sensitivity or IGF-1 levels [3]