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How meningococcus obtains L-cysteine is crucial to understanding its survival mechanisms in host cells, as cysteine is used for protein and glutathione synthesis, as well as being the main sulfur source for a variety of other molecules, such as biotin, coenzyme A, lipoic acid, and other cysteine derivatives important for protection from oxidative stress

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Recent findings revealed that MYC also modulates autophagy in a highly context-dependent manner, functioning as either a suppressor or activator depending on oncogenic signaling, metabolic state, and tissue type

Netrin-1 upregulates GPX4 and prevents ferroptosis after traumatic brain injury via the UNC5B/Nrf2 signaling pathway

2018 Nov Amir Sharabi, Eytan Cohen, Jaqueline Sulkes, Moshe Garty