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This response was more limited to the gut, so may have helped more in people with gastrointestinal issues like irritable bowel syndrome and Crohns

After 4 weeks, they assess the patients tolerance and severity of side effects and adjust the dosage accordingly

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According to the Mayo Clinic, Peripheral nerves send messages from your brain and spinal cord to the rest of your body, helping you do things such as sensing that your feet are cold and moving your muscles so that you can walk. Peripheral Neuropathy is common in individuals over the age of 55 and refers to general diseases or malfunctions of the nerves as they try to carry messages from the brain and spinal cord to the rest of the body

Annu Rev Genomics Hum Genet (2017) 18:16787