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& Battistelli, B

Wild-type IDH1 maintains NSCLC stemness and chemoresistance through activation of the serine biosynthetic pathway

IM shots offer a fast, convenient alternative to IV drips for nutrient delivery

doi: 10.1111/cas.12445 112 LiuJZhangHJiaLSunH

This aligns with the fact that overexpression of PPAR coactivator 1-alpha (PGC-1), a regulator of mitochondrial biogenesis, increases the generation of CD8 central memory T cells and, in general, improves murine immune responses following infection, immunization, and in the generation of antitumor immunity (131)

While it decreases ROS generation by enhancing antioxidant enzyme activity, DPQ has also been associated with detrimental effects, including increased DNA damage and apoptosis in cardiomyocytes 170